Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
| Upregulated in class | wtNotch |
| GeneSet | BIOCARTA_TOLL-LIKE RECEPTOR PATHWAY |
| Enrichment Score (ES) | -0.6545767 |
| Normalized Enrichment Score (NES) | -1.6140437 |
| Nominal p-value | 0.0072115385 |
| FDR q-value | 0.1917982 |
| FWER p-Value | 0.921 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PGLYRP1 | 6760242 | 1527 | 1.254 | -0.0360 | No | ||
| 2 | NFKBIA | 1570152 | 1757 | 1.101 | -0.0078 | No | ||
| 3 | CD14 | 5570600 | 2022 | 0.987 | 0.0143 | No | ||
| 4 | IRAK1 | 4120593 | 3185 | 0.499 | -0.0298 | No | ||
| 5 | TLR4 | 1690167 2650369 3850333 | 3432 | 0.431 | -0.0272 | No | ||
| 6 | TLR2 | 5050162 | 3442 | 0.429 | -0.0119 | No | ||
| 7 | FOS | 1850315 | 3645 | 0.386 | -0.0086 | No | ||
| 8 | MAP2K3 | 5570193 | 5010 | 0.191 | -0.0749 | No | ||
| 9 | JUN | 840170 | 6110 | 0.114 | -0.1299 | No | ||
| 10 | TLR9 | 670093 670706 | 9878 | 0.014 | -0.3321 | No | ||
| 11 | ECSIT | 3850170 | 9945 | 0.013 | -0.3352 | No | ||
| 12 | MYD88 | 2100717 | 9972 | 0.012 | -0.3361 | No | ||
| 13 | PPARA | 2060026 | 10473 | 0.004 | -0.3629 | No | ||
| 14 | TLR6 | 510102 3390148 | 11610 | -0.015 | -0.4235 | No | ||
| 15 | TLR3 | 6760451 | 12583 | -0.036 | -0.4744 | No | ||
| 16 | IKBKG | 3450092 3840377 6590592 | 13790 | -0.082 | -0.5363 | No | ||
| 17 | RELA | 3830075 | 14534 | -0.138 | -0.5713 | No | ||
| 18 | MAP2K6 | 1230056 2940204 | 14593 | -0.145 | -0.5691 | No | ||
| 19 | TLR7 | 3140300 | 14714 | -0.158 | -0.5697 | No | ||
| 20 | TIRAP | 60129 6400097 | 15366 | -0.277 | -0.5945 | No | ||
| 21 | TRAF6 | 4810292 6200132 | 16483 | -0.654 | -0.6305 | Yes | ||
| 22 | MAPK8 | 2640195 | 16603 | -0.718 | -0.6105 | Yes | ||
| 23 | LY96 | 630519 | 17152 | -1.032 | -0.6020 | Yes | ||
| 24 | EIF2AK2 | 870239 | 17287 | -1.132 | -0.5675 | Yes | ||
| 25 | MAP3K14 | 5890435 | 17297 | -1.137 | -0.5261 | Yes | ||
| 26 | MAPK14 | 5290731 | 17315 | -1.150 | -0.4847 | Yes | ||
| 27 | MAP3K7IP1 | 2120095 5890452 6040167 | 17322 | -1.155 | -0.4425 | Yes | ||
| 28 | TOLLIP | 5340601 6200465 | 17376 | -1.210 | -0.4008 | Yes | ||
| 29 | IKBKB | 6840072 | 17404 | -1.233 | -0.3569 | Yes | ||
| 30 | MAP3K7IP2 | 2340242 | 17493 | -1.315 | -0.3132 | Yes | ||
| 31 | MAP2K4 | 5130133 | 18021 | -1.863 | -0.2730 | Yes | ||
| 32 | MAP3K7 | 6040068 | 18082 | -1.929 | -0.2053 | Yes | ||
| 33 | CHUK | 7050736 | 18503 | -2.821 | -0.1240 | Yes | ||
| 34 | MAP3K1 | 5360347 | 18584 | -3.533 | 0.0017 | Yes |
